In should be emphasized for the control of various

In conclusion, henna
has many traditional and commercial uses, the most common being as a dye for
hair, skin and fingernails, as a dye and preservative for leather and cloth,
and as an anti-microbacterial. The skin has an comples flora which can
breakdown the integrity of the skin when the immune defense is compromised. We have
conclude that Lawsonia Inrmis posses high antimicrobacterial activity against
P.eruginosa. By using cream or soaps incorporating henna active ingredients may
be great advantage for hygiene purposes for both physicians and patients  in hospitals especially in intensive care
units or infectious disease units where immuno-compromised patients are treated.
L. inermis should be emphasized for the control of various diseases.
Henna imbibing a tremendous potential deserves a special attention of the
scientific fraternity to emerge as a milestone for medical science of this
millennium due to its various medicinal uses. Further evaluation needs to be
carried out on L. inermis L. in order to explore the concealed areas and their
practical clinical applications, which can be used for the welfare of the
mankind. Henna is a traditional
cosmetic agent and is used worldwide. It is used worldwide not only as a
cosmetic agent to stain the hair, skin and nails but also is applied to the
body on lesions in the treatment of seborrheic dermatitis or fungal infections.



The  World
 Health  Organization 
(WHO)   is discovering about  medical 
plants  and  traditional medicines  and 
exploitation  of  scientific validity  of  the   herbal
 medicines  that has been used  since  
traditions.  Herbal   medicine 
are  great  demand  in
 developing  countries  for  primary
  healthcare.  There are some updated  information  on  various
 aspects  of  Lawsonia inermis  a  plant
 that  is  used
 all  over  the  world  that  has  been
compiled and review.  This  plant  is   known
 as  Henna  or
 Mhendi  and live  in  tropical  and  subtropical  areas. It plays appreciable role in Ayurvedic
and natural herbal medicines in ancient history of India.  The archaeological  evidence  from  Egypt    that  Lawsonia inermis (henna)  used  to
 treat  skin  ailments  and  hair
 colour  five  thousand  years  ago.  There  are
 some  evidence  that  brides  marked  their  hands  and  feet  with  henna
 for  weddings  in  Mesapotamia  and  the
 Eastern  Mediterranean.  In  the  19th and  early  20th
 centuries,  most  of
 the  henna  used
 by  Europe  and
 the  USA  was
 grown in  Egypt.  Lawsonia inermis   is  biennial  dicotyledonous  herbaceous  shrub  which
 in  native  of  North  Africa  and  South-
 West  Asia,  the  plant  is
 now  widely  cultivated through  out  the
 tropics  as  an  ornamental  and  dye
 plant. In  medicinally,  the  leaves
 and aerial  parts  of  Lawsonia inermis  are  frequently
 used  as  herbal  remedy  for
 human disorders  such  as
 rheumatoid  arthritis,  headache,  ulcers,  diarrhea,  leprosy,  fever, leucorrhoea,  diabetes,  cardiac disease,  hepatoprotective  and  as  a  coloring  agent  along
 with  other  herbal  medicines  (Sarwat et  al., 2012, Gul et al., 2012)

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In this study, Lawsonia
inermis has demonstrated antibacterial activity against the bacterial
strains that have highest antibacterial activity against Pseudomonas Aeruginosa a species which is invasive and
toxigenic. Pseudomonas aeruginosa is a Gram-negative, aerobic bacterium that has been found
in water and soil. It is gastrointestinal tract of  human beings and  the skin is a normal flora. This bacterium is
an opportunistic pathogen which important microorganisms in nosocomial
infections in immune-compromised patients that have  malignancies, cystic fibrosis and burns with
multiple pathogenic factors and  high
rate of resistance towards antibiotics. This is because the presence of
glycocalyx in cellular membrane is responsible for binding of the bacterium to
the host cell easily, formation of biofilm and protection of bacteria against
penetration of antimicrobial agents and phagocytic
system.  aeruginosa
is the most commonly known as isolated nosocomial pathogen, where all acquired
infections about 10%. Hospitalized patients was increase up to 20%  upon in the gastrointestinal carriage rates
due Pseudomonas aeruginosa in
immunocompromised patints with diabetes. Treatment for  P.
aeruginosa infection is usually by intravenous combinations of
antibiotic but it doesn’t work. So, lawsonia
inermis (henna) can cure  Peudomonas Aeruginosa infections.
Fresh henna leaves demonstrated the highest anti-microbial activity of P. aeruginosa . The inherent characteristics
of the fully grown plants is probably due to the maturity of its chemically
active constituents for example  quinines. 
The added presence of chlorophyll may be attributed in one of the
constituents of fresh leaves that are known to possess antimicrobial activity.
5% weight of the compound (2-hydroxy-1,4-naphthoquinone) contain in henna
leaves. These are the methods to determine anti- microbacterial activity by
henna against P.aeruginosa.
100g fresh leaves and dry leaves and 50g of fresh seeds and dry seeds are
soaked seperatelly in 500ml of  ethanol
for 3 days. The mixture was filtered and extract the crude that has been
collected then heated at 48? in a water bath to evaporate its liquid content.
The dry crude henna was extracted and tested for its antimicrobacterial
activity. Although the fresh and dry seeds demonstrated antibacterial activity
against P. aeruginosa, our fresh henna leaves
demonstrated the highest anti-P. aeruginosa activity.
 The most effective against the spectrum
of bacterial isolates tested is strikingly henna’s leaves  as compared with its  seeds. The two ketone substitutions contains aromatic
rings contain. They are characteristically highly active and ubiquitous in
nature. In addition,  provide a source
with  stable free radicals, to complex
irreversibly with nucleophilic amino acids in proteins whichly known as quinones  . The  antimicrobial effects is great on the
potential range of quinone. Lawsonia
Inermis has possess high antibacterial activities against P.
aeruginosa. Numerous free hydroxyl ions are capable to combine
with the carbohydrates and proteins during the antimicrobial activity in the
bacterial cell wall. The antibacterial activity of Lawsonia Inermis extraction 
of alcoholic and oily were more effective results in a previous study.
Among all of the tested microorganisms, the methanolic extraction of L. inermis was more active against
S. aureus and Proteus sp. than others. These results are similar to that
obtained from a recent study. Other investigations showed that Henna is
effective against different microorganisms especially against P. aeruginosa.  This clearly shown that lawsonia inermis can
cure skin infections by applying the extraction of  henna’s leaves on the infenctinous skin.